You can now add me to the list of those receiving that damn Error 12 upon save. My game was fine (with the exception of a bad CC item which has been removed) and never crashed once. I've never had any problems at all. Now all of a sudden it absolutely will not let me save. I just keep receiving error 12 over and over. I'm on Windows XP, and I have the dreaded patch.
I'm fully convinced that these errors and CTD's are caused by the file's size. (Gamesave bloating??)
I believe this to be the case as well. My saved game file is now huge. I'm going to remove some things and try the compressor on all of my downloads. Maybe that will help. If I can get the save to work again, I'll also turn on the auto-save on the Awesome Mod.
EA needs to fix this damn game. This is ridiculously frustrating.