Same here. After patching the game to v.1.4.6 it started that CTD-thing. I tried to run it without mods and it crashed again. Since I am running Sims 3 on WinXP 64 I changed to another partition (my pc is set up as multi-boot) with Win XP 32 SP2 installed and got the same results after updating to 1.4.6. It's crashing again and again on both Systems which makes the game unplayable for me. It either happens at save (instead of error 12 or 13 code which I have seen a lot in the past now it crashes to desktop) or it happens somewhere within the game most likely when I move the mouse (i.e. the camera) fast and over a longer distance. 

So I read that long list of fixes and so-called improvements but I couldn't find any message about what are the two FATTEST bugs in the game:
1. The save issue (error code 13 and 12... and endless saves)
2. The stereos that are not playing.
(3. crash on launch)

Does that mean that EA totally ignores the hundreds or thousands of reports about this issues that can be found on the net?
Maybe they are feeling so much shame for this substantial bugs (ever heard of an official game release where the saves wouldn't work?) that they didn't even mention that they (hopefully) fixed it now.
Since I didn't install the patch yet, is there anyone of you who can confirm the save or radio bugs do still happen?