The Prima guide confirms the apples/watermelons theory. It also says that watching children's TV & listening to kids' music ups your chance of multiples.
Pssh. Prima Guide cannot "confirm" anything. The Prima Guide is far more often wrong than right.
Fair enough.
What testing I have done thus far ingame seems to confirm as well, but I haven't been testing as extensively some of the folks here have, so take it with a grain of salt. I had a female subsist primarily on apples or watermelon for the duration of her four pregnancies, so it's a rather small data pool (some spaghetti was allowed for cravings). The three apple-based pregnancies resulted in boys. The watermelon-based pregnancy was accompanied by copious amounts of children's music and resulted in twin girls. Feel free to add that to the data pool if you want.