What sucks is, I'm on a Mac. So it's not just a lack of awesomeness that keeps me from using Paladin's.
You can move your Mac "The Sims 2" directory in and out of a Windows system. I do this from time to time to make in-game facial surgeries on insufficiently good looking Sims be inheritable by those Sims' offspring.
If you are unaverse to Arring VMware or Parallels (for Intel Macintoys) or VirtualPC (for PowerPC Macintoys) and can install a (
preferably Arred!) Windows XP in that, then you can install a Windows version of TS2 (and all the same EPs you have) in that. DO NOT RUN THE GAME IN THE VIRTUAL MACHINE.
You can then use Finder > File > Compress in your user Documents/EA Games/The Sims 2 directory, which creates a .zip, which you can import (probably just by dragging) into your Windows virtual machine My Documents directory. Unzip it there, and then install SimPE and whatever other tools you like.
Edit, fold, spindle, mutilate and conflict checker at will. You could probably even run the game, but I don't trust EAxis code enough to let it touch anything I might possibly want to reimport into the Aspyr-fixed version on my Mac -- I have horrible visions of unnecessary byte sex flipping, catastrophic XML rewriting, and especially arbitrary file name changing. If you're *just* doing conflict checking or the "manual binary search" method, then you're not going to reimport anything, so running the game or deleting files willy-nilly is harmless. Just don't reimport the result.
When you're done in the rich world of third party external tools that are sadly unlikely ever to be ported to the Mac, *if* you're made changes you want to use in your game, just zip up the Windows game directory, import the Windows-made .zip back into your Mac, delete your old Documents/EA Games/The Sims 2 directory, and finally unzip the Windows-made .zip in Documents/EA Games.
Finally, fire up your Mac game, visit several lots where you can see if the changes you made work (exit without saving from the first couple of those unless you are very trusting), and hopefully It Just Worked.
Be sure to use backups. Occasionally zipping up the The Sims 2 directory (and putting the date and some notes into the file name) is a good policy and has saved my bacon (or at least my game) a couple of times, as has Time Machine.